fission_yeast | 遺伝子名 | GTPase-activating protein |
同義語(エイリアス) | Ras GTPase-activating protein; GTPase activating protein Gap1; src1; gap1; SPBC646.12c | |
SWISS-PROTのID | SWISS-PROT:P33277 | |
EntrezGeneのID | --- | |
その他のDBのID | GeneDB_SPombe:SPBC646.12c |
fly | 遺伝子名 | GTPase-activating protein |
同義語(エイリアス) | Ras-GAP; more inner photoreceptors; rasGAP; Gap; sxt: sextra; seven extra; gap1; Gap1; gap; mip: more inner photoreceptors; sextra; CG6721; GTPase-activating protein 1; Ras GTPase-activating protein; mip; GAP1; rI533; GAP; sxt | |
SWISS-PROTのID | SWISS-PROT:P48423 | |
EntrezGeneのID | EntrezGene:39158 | |
その他のDBのID | FlyBase:FBgn0004390 |
human | 遺伝子名 | GTPase-activating protein |
同義語(エイリアス) | CMAVM; RASGAP; RASA1; RasGAP; Ras p21 protein activator; RASA; Ras GTPase-activating protein 1; PKWS; DKFZp434N071; GAP; CM-AVM; p120GAP | |
SWISS-PROTのID | SWISS-PROT:P20936 | |
EntrezGeneのID | EntrezGene:5921 | |
その他のDBのID | HGNC:9871 |
rat | 遺伝子名 | GTPase-activating protein |
同義語(エイリアス) | Rasa1; GAPX; RAS p21 protein activator; Rasa; RasGAP; Ras p21 protein activator; Ras GTPase-activating protein 1; RAS p21 protein activator 1; GAP; p120GAP | |
SWISS-PROTのID | SWISS-PROT:P50904 | |
EntrezGeneのID | EntrezGene:25676 | |
その他のDBのID | RGD:3537 |
yeast | 遺伝子名 | GTPase-activating protein |
同義語(エイリアス) | GYP5; GTPase-activating protein GYP5; YPL249C | |
SWISS-PROTのID | SWISS-PROT:Q12344 | |
EntrezGeneのID | EntrezGene:855827 | |
その他のDBのID | SGD:S000006170 |
yeast | 遺伝子名 | GTPase-activating protein |
同義語(エイリアス) | YFL027C; GYP8; GTPase-activating protein GYP8 | |
SWISS-PROTのID | SWISS-PROT:P43570 | |
EntrezGeneのID | EntrezGene:850517 | |
その他のDBのID | SGD:S000001867 |
yeast | 遺伝子名 | GTPase activating protein |
同義語(エイリアス) | Inhibitory regulator protein IRA2; GLC4; CCS1; YOL081W; IRA2; O0985 | |
SWISS-PROTのID | SWISS-PROT:P19158 | |
EntrezGeneのID | EntrezGene:854073 | |
その他のDBのID | SGD:S000005441 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/05/30 15:30 UTC 版)
GTPase-Activating Proteins, or GAPs, or GTPase-Accelerating Proteins are a family of regulatory proteins whose members can bind to activated G proteins and stimulate their GTPase activity, with the result of terminating the signaling event. GAPs are also known as regulator of G protein signaling proteins, or RGS proteins, and these proteins are crucial in controlling the activity of G proteins. Regulation of G proteins is important because these proteins are involved in a variety of important cellular processes. The large G proteins, for example, are involved in transduction of signaling from the G protein-coupled receptor for a variety of signaling processes like hormonal signaling, and small G proteins are involved in processes like cellular trafficking and cell cycling. GAP’s role in this function is to turn the G protein’s activity off. In this sense, GAPs function is opposite that of guanine nucleotide exchange factors (GEFs), which serve to enhance G protein signaling.