a protein involved in normal cell growth. it is found on some types of cancer cells, including breast and ovarian. cancer cells removed from the body may be tested for the presence of her2/neu to help decide the best type of treatment. her2/neu is a type of receptor tyrosine kinase. also called c-erbb-2, human egf receptor 2, and human epidermal growth factor receptor 2.
human | 遺伝子名 | Her-2/neu |
同義語(エイリアス) | c-erb B2; HER2; c-erbB-2; ErbB2/neu; NGL; C-erbB-2; NEU; HER2-neu; NEU proto-oncogene; p185erbB2; HER-2/neu; c-erbB2/neu; c-erbB-2/neu; Her2/neu; Tyrosine kinase-type cell surface receptor HER2; HER 2; HER-2; Receptor tyrosine-protein kinase erbB-2 precursor; TKR1; ERBB2; MLN 19; ErbB-2/neu | |
SWISS-PROTのID | SWISS-PROT:P04626 | |
EntrezGeneのID | EntrezGene:2064 | |
その他のDBのID | HGNC:3430 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/06/18 10:44 UTC 版)
HER2/neu (also known as ErbB-2) stands for "Human Epidermal growth factor Receptor 2" and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2/neu has also been designated as CD340 (cluster of differentiation 340) and p185. It is encoded by the ERBB2 gene.