出典:Wikipedia
出典:『Wikipedia』 (2011/07/01 04:57 UTC 版)
Tapentadol (trade name Nucynta) is a centrally acting analgesic with a dual mode of action as an agonist at the μ-opioid receptor and as a norepinephrine reuptake inhibitor. While its action reflects aspects of tramadol and morphine its ability to kill pain is more on the order of hydrocodone and oxycodone, so not as weak as tramadol but not as strong as morphine. Tapentadol is a new molecular entity that is structurally similar to tramadol (Ultram). It has opioid and nonopioid acitivity in a single compound.