出典:Wikipedia
出典:『Wikipedia』 (2011/02/27 20:52 UTC 版)
The hepatocyte cell adhesion molecules 1 and 2 (HEPACAM 1 and 2) are members of the immunoglobulin family of adhesion genes. HEPACAM1 is involved in negative cell cycle regulation via p53, p21 and p27 signalling but also mediates increased human breast cancer cell spread. Metastatic canine mammary carcinoma and their metastases are characterized by decreased HEPACAM2 but unchanged HEPACAM2 expression levels when compared to normal glands.