英和和英

名詞

iPSC (複数形 iPSC または iPSCs)

1. (biology) Initialism of induced pluripotent stem cell.
   • 2009, Essentials of stem cell biology, edition 2, Robert Paul Lanza (editor), page 30:

     The fact that only a small fraction of cells infected with the reprogramming factors form iPSC colonies indicates that direct reprogramming is a stochastic process.

   • 2010, Michael Roßbach, Manal Hadenfeld, and Oliver Brüstle, Industrial Applications of Stem Cells, in Translational Stem Cell Research: Issues Beyond the Debate, Kristina Hug, Göran Hermerén (editors), page 91:

     One of the most promising routes in this regard is the generation of induced pluripotent stem cells (iPSC) by reprogramming cells.

   • 2010, G. Sun et al, in Biomaterials as Stem Cell Niche, Krishnendu Roy (editor), page 202:

     ECs Derived from ESC and iPSC

   • 2011, M. A. Hayat (editor), Stem Cells and Cancer Stem Cells: Therapeutic Applications in Disease and Injury, volume 1, page 10:

     [...] the propensity of stem cells to form teratoma following transplantation is still another major obstacle in using iPSC for disease therapy.

   • 2015, Paull, D. et al., "Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells", Nature Methods, vol. 12, no. 9, pg. 885 (abstract):

     The preparation of somatic cells, their reprogramming and the subsequent verification of iPSC pluripotency are laborious, manual processes [....]