出典:Wikipedia
出典:『Wikipedia』 (2009/12/22 19:52 UTC 版)
The Caenorhabditis elegans sel-12 gene encodes a multi-pass transmembrane domain protein that is similar to human presenilin. sel-12 positively regulates the lin-12 and glp-1 Notch signaling pathways during hermaphrodite gonadal, vulval, and germline development. sel-12 also plays a role in thermotaxis (the nematode worm prefers a certain temperature and moves accordingly).