fly | 遺伝子名 | presenilin |
同義語(エイリアス) | DmPS; PS1; pres; Presenilin homolog; DrosPS; dPS; dPresenilin; DPsn; Dps; psn; Dpresenilin; CG5868; Psn; CG18803; l(3)77CDb; DPS; Presenilin | |
SWISS-PROTのID | SWISS-PROT:O02194 | |
EntrezGeneのID | EntrezGene:40260 | |
その他のDBのID | FlyBase:FBgn0019947 |
zfish | 遺伝子名 | presenilin |
同義語(エイリアス) | zfPS1; psen1; PS1; psen; pre1; zf-PS1; Zf-PS1; Presenilin-1 | |
SWISS-PROTのID | SWISS-PROT:Q9W6T7 | |
EntrezGeneのID | EntrezGene:30221 | |
その他のDBのID | ZFIN:ZDB-GENE-991119-4 |
本文中に表示されているデータベースの説明
出典:Wiktionary
presenile + -in, since they were first identified in screens for mutations causing early onset forms of familial Alzheimer's disease.
出典:Wikipedia
出典:『Wikipedia』 (2011/06/20 14:42 UTC 版)
Presenilins are a family of related multi-pass transmembrane proteins that function as a part of the gamma-secretase intramembrane protease complex. Vertebrates have two presenilin genes, called PSEN1 (located on chromosome 14 in humans) that encodes presenilin 1 (PS-1) and PSEN2 (on chromosome 1 in humans) that codes for presenilin 2 (PS-2). Both genes show conservation between species, with little difference between rat and human presenilins. The nematode worm C. elegans has two genes that resemble the presenilins and appear to be functionally similar, sel-12 and hop-1.