Wiktionary英語版

出典:Wiktionary

thiomer

語源

thio- +‎ -mer

名詞

thiomer (複数形 thiomers)

  1. (organic chemistry) A thiolated polymer
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ウィキペディア英語版

出典:Wikipedia

Thiomer

出典:『Wikipedia』 (2009/02/21 20:02 UTC 版)

英語による解説

ウィキペディア英語版からの引用
引用

Thiolated polymers or designated thiomers are mucoadhesive polymers which display thiol group bearing side chains. In brief, low molecular mass thiol group bearing compounds are covalently bound to a polymeric backbone. This backbone consists of well-established and safe polymers such as chitosan or poly(acrylic acid). It has been demonstrated in various studies, that thiomers exhibit mucoadhesive, permeation enhancing, controlled release as well as enzyme and efflux pump inhibitory properties. These features make the thiomer technology highly interesting for non-invasive delivery routes, including in first instance the oral but also the nasal, buccal and vaginal route. Thiomers can be directly compressed to tablets or given as solutions. Furthermore thiomer based micro- and nanoparticles have already been developed.

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