Hsromegaとは 意味・読み方・使い方

The heat shock gene hsromega is a long non-coding RNA which produces a number of transcripts. These transcripts include a nuclear transcript, hsromega-n, which is detected as small speckles in the interchromatin space and co-localises with heterogeneous nuclear RNA-binding proteins (hnRNPs). Hsromega-n interacts directly and indirectly with a number of regulatory proteins including hnRNPs, cAMP response element binding binding protein (CBP), proteasome, and Drosophila inhibitor of apoptosis protein 1 (DIAP1). Through these interactions, it has roles in the regulation of apoptosis and the suppression of poly(Q) toxicity.