Plasmepsinとは 意味・読み方・使い方

Plasmepsins are a class of at least 10 enzymes (EC 3.4.23.38 and EC 3.4.23.39) produced by the plasmodium parasite. There are ten different isoforms of these proteins and ten genes coding them respectively in plasmodium falciparum (Plm I, II, III, IV, V, VI, VII, IX, X and HAP). It has been suggested that the plasmpesin family is smaller in other human plasmodium species. Expression of Plm I, II, IV, V, IX, X and HAP occurs in erythrocytic cycle, and expression of Plm VI, VII, VIII, occurs in exoerythrocytic cycle. Through their haemoglobin-degrading activity, they are an important cause of symptoms in malaria sufferers. Consequently this family of enzymes is a potential target for antimalarial drugs.the aspartic protease of Plasmodiumspecies are known as Plasmepsins