a drug used to cause a loss of feeling and awareness and to induce sleep in patients having surgery. it is also being studied in the treatment of nerve pain caused by chemotherapy. ketamine blocks pathways to the brain that are involved in sensing pain. it is a type of general anesthetic. also called ketalar and ketamine hydrochloride.
出典:Wiktionary
出典:『Wiktionary』 (2026/03/11 15:03 UTC 版)
ketamine (countable and uncountable, plural ketamines)
出典:Wikipedia
出典:『Wikipedia』 (2011/08/11 17:13 UTC 版)
Ketamine is a drug used in human and veterinary medicine. Its hydrochloride salt is sold as Ketanest, Ketaset, and Ketalar. Pharmacologically, ketamine is classified as an NMDA receptor antagonist. At high, fully anesthetic level doses, ketamine has also been found to bind to opioid μ receptors type 2 in cultured human neuroblastoma cells, however without agonist activity, and to sigma receptors in rats. Also, ketamine interacts with muscarinic receptors, descending monoaminergic pain pathways and voltage-gated calcium channels. Like other drugs of this class such as tiletamine and phencyclidine (PCP), it induces a state referred to as "dissociative anesthesia" and is used as a recreational drug.