| human | 遺伝子名 | Nod1 |
| 同義語(エイリアス) | caspase recruitment domain family, member 4; Caspase recruitment domain-containing protein 4; CARD4; Protein Nod1; NOD1 | |
| SWISS-PROTのID | SWISS-PROT:Q9Y239 | |
| EntrezGeneのID | EntrezGene:10392 | |
| その他のDBのID | HGNC:16390 |
| mouse | 遺伝子名 | Nod1 |
| 同義語(エイリアス) | F830007N14Rik; Caspase recruitment domain-containing protein 4; C230079P11; caspase recruitment domain 4; Card4 | |
| SWISS-PROTのID | SWISS-PROT:Q8BHB0 | |
| EntrezGeneのID | EntrezGene:107607 | |
| その他のDBのID | MGI:1341839 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/01/17 14:46 UTC 版)
Nucleotide-binding oligomerization domain-containing protein 1 is a protein that in humans is encoded by the NOD1 gene. NOD1 protein contains a caspase recruitment domain (CARD). NOD1 is a member of NOD-like receptor protein family and is a close relative of NOD2. NOD1 is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. Nod1 interacts with RIPK2 through the CARDs of both molecules (See the structure of the NOD1 CARD in the right panel). Stimulation of NOD1 by iE-DAP containing molecules results in activation of the transcription factor NF-κB.