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• open label

形容詞

open-label (not comparable)

1. (medicine, sciences, biology) Not withholding information from the participants of a clinical trial, as opposed to double-blind.
   • 2021 September 15, Robert Langreth, “Moderna says analysis shows COVID vaccine immunity may wane”, in The Boston Globe‎, retrieved 10 September 2026:

     The company said it found that people who received the vaccine earlier had more than a 50 percent higher rate of symptomatic breakthrough infections in July and August, compared with those who were inoculated later. The unpublished analysis is from the so-called open-label portion of Moderna’s trial, after the participants who had been given a placebo were offered the actual vaccine. Since the trial is no longer blinded, this type of additional analysis is considered less rigorous than the original study.

   • 2022 October 8, Zoë Corbyn, quoting Kathryn T Hall, “Placebos expert Kathryn T Hall: ‘The effect can rival painkillers like ibuprofen or even morphine’”, in The Guardian‎, retrieved 10 September 2026:

     Trademarked placebo pills such as Zeebo are also available, although they have not been tested in clinical trials. To me, what suggests a path forward are the small clinical trials of so-called open-label placebos (OLPs) – in which the patient knows they are receiving a placebo and the rationale for how they can work is explained. The trials, for conditions such as back pain, cancer-related fatigue and IBS, report significant benefit of OLPs compared with no treatment.

   • 2023 October 10, Ted J. Kaptchuk, “No Better Than a Placebo”, in The New York Times‎, retrieved 10 September 2026:

     In another blow to the concept that concealment is required for placebo effects, my team recently published a study comparing open-label placebos and double-blind placebos in irritable bowel syndrome and found no significant difference between the two.