a drug used to treat breast cancer, ovarian cancer, and aids-related kaposi sarcoma. it is also used together with another drug to treat non-small cell lung cancer. paclitaxel is also being studied in the treatment of other types of cancer. it blocks cell growth by stopping cell division and may kill cancer cells. it is a type of antimitotic agent. also called taxol.
出典:Wiktionary
出典:『Wiktionary』 (2024/06/09 21:23 UTC 版)
paclitaxel (uncountable)
出典:Wikipedia
出典:『Wikipedia』 (2011/07/20 08:46 UTC 版)
Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a U.S. National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it taxol. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to paclitaxel and the BMS compound is sold under the trademark TAXOL. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent. A newer formulation, in which paclitaxel is bound to albumin, is sold under the trademark Abraxane.