| worm | 遺伝子名 | TOPoisomerase |
| 同義語(エイリアス) | DNA topoisomerase 3; CE28138; Y56A3A.27.2; WP:CE28138; Y56A3A.27.1; top-3; DNA topoisomerase III; Y56A3A.27 | |
| SWISS-PROTのID | SWISS-PROT:O61660 | |
| EntrezGeneのID | EntrezGene:176631 | |
| その他のDBのID | WormBase:WBGene00006596 |
| worm | 遺伝子名 | TOPoisomerase |
| 同義語(エイリアス) | M01E5.5b; CE12284; M01E5.5; M01E5.5a; WP:CE12282; top-1; WP:CE12284; CE12282 | |
| SWISS-PROTのID | --- | |
| EntrezGeneのID | EntrezGene:266847 | |
| その他のDBのID | WormBase:WBGene00006595 |
本文中に表示されているデータベースの説明
出典:Wiktionary
出典:『Wiktionary』 (2025/10/01 17:08 UTC 版)
topoisomerase (plural topoisomerases)
出典:Wikipedia
出典:『Wikipedia』 (2011/05/30 21:36 UTC 版)
Topoisomerases (type I: EC 5.99.1.2, type II: EC 5.99.1.3) are enzymes that unwind and wind DNA, in order for DNA to control the synthesis of proteins, and to facilitate DNA replication. The enzyme is necessary due to inherent problems caused by the DNA's double helix. The structure of DNA is a double-stranded helix, wherein the four bases, adenine, thymine, guanine, and cytosine are paired and stored in the center of this helix. While this structure provides a stable means of storing the genetic code, Watson and Crick noted that the two strands of DNA are intertwined, and this would require the two strands to be untwisted in order to access the information stored. However they also foresaw that there would be some mechanism to overcome this problem.