出典:Wiktionary
出典:『Wiktionary』 (2026/05/04 15:58 UTC 版)
telomerase (plural telomerases)
出典:Wikipedia
出典:『Wikipedia』 (2011/07/05 21:11 UTC 版)
Telomerase is an enzyme that adds DNA sequence repeats ("TTAGGG" in all vertebrates) to the 3' end of DNA strands in the telomere regions, which are found at the ends of eukaryotic chromosomes. This region of repeated nucleotide called telomeres contains non-coding DNA material and prevents constant loss of important DNA from chromosome ends. As a result, every time the chromosome is copied only 100-200 nucleotides are lost, which causes no damage to the organism's DNA. Telomerase is a reverse transcriptase that carries its own RNA molecule, which is used as a template when it elongates telomeres, which are shortened after each replication cycle.
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