| human | 遺伝子名 | C-ANCA |
| 同義語(エイリアス) | PRTN3; P29; NP-4; C-ANCA antigen; PR3; Wegener autoantigen; MBT; Myeloblastin precursor; MBN; AGP7; PR-3; Neutrophil proteinase 4; ACPA; Leukocyte proteinase 3 | |
| SWISS-PROTのID | SWISS-PROT:P24158 | |
| EntrezGeneのID | EntrezGene:5657 | |
| その他のDBのID | HGNC:9495 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/05/13 22:56 UTC 版)
c-ANCAs, or Cytoplasmic antineutrophil cytoplasmic antibodies, are a type of autoantibody, an antibody produced by the body that acts against one of its own proteins. These antibodies show a diffusely granular, cytoplasmic staining pattern under microscopy. This pattern results from binding of ANCAs to antigen targets throughout the neutrophil cytoplasm, the most common protein target being proteinase 3 (PR3). For example, PR3 is the most common antigen target of ANCA in patients with Wegener's granulomatosis. In active Wegner's, c-ANCA is found in over 90% of the time. Other antigens may also occasionally result in a c-ANCA pattern.