英和和英

出典:『Wikipedia』 (2011/08/12 14:11 UTC 版)

英語による解説

引用

A nicotine patch is a transdermal patch that releases nicotine into the body through the skin. It is used as an aid in nicotine replacement therapy (NRT), a process for smoking cessation. The first published study of the pharmacokinetics of a transdermal nicotine patch in humans was authored by Jed E. Rose, Ph.D., Murray E. Jarvik, M.D., Ph.D. and K. Daniel Rose, M.D., in the journal Drug and Alcohol Dependence (vol. 13, pp.209-213, 1984). This was followed by publication of results of a study of smokers showing that a transdermal nicotine patch reduced craving for cigarettes (Rose JE, Herskovic JE, Trilling Y and Jarvik ME, Clinical Pharmacology and Therapeutics, vol. 38, pp. 450-456, 1985). The University of California filed a patent application in April, 1985 that was granted in 1991 (U.S. Patent #4,920,989). However, a competing patent application, filed by Dr. Frank T. Etscorn III, was issued on July 1, 1986 (U.S. Patent #4,597,961). Subsequently, the U.S. Patent Office declared an interference action and, on September 29, 1993, issued a priority decision in favor of the Rose et al. patent.