英和和英

語源

From Wisconsin Alumni Research Foundation +‎ (coum)arin.

発音

• (Received Pronunciation) IPA: /ˈwɔː.fə.ɹɪn/
• (General American) IPA: /ˈwɔɹ.fəɹ.ɪn/

名詞

warfarin (countable and uncountable, plural warfarins)

1. (pharmacology) A coumarin salt, warfarin sodium, found in certain clovers, that retards blood coagulation:
   • 2015 July 29, Carville G. Bevans et al., “Phylogeny of the Vitamin K 2,3-Epoxide Reductase (VKOR) Family and Evolutionary Relationship to the Disulfide Bond Formation Protein B (DsbB) Family”, in Nutrients‎, volume 7, →DOI:

     In the case of pathological hypercoagulative conditions such as thrombosis and embolism, 4-hydroxycoumarin based oral anticoagulants, including warfarin as a well-known example, are administered to block the enzymatic function of VKORC1, effectively diminishing turnover of the vitamin K cycle.

   1. Manufactured as a pharmaceutical drug and used in low dosage, with regular monitoring, for the prevention of thrombosis and embolism.
   2. Manufactured as a chemical, used in high dosage as a pesticide.

派生語

参考

• blood thinner
• brodifacoum

参照

• “warfarin”, in Lexico, Dictionary.com; Oxford University Press, 2019–2022.
• “warfarin”, in Merriam-Webster Online Dictionary, Springfield, Mass.: Merriam-Webster, 1996–present.