Amyloid plaqueとは 意味・読み方・使い方

To develop a method for preventively and therapeutically treating symptoms characterized by formation of amyloid plaque.例文帳に追加

アミロイドプラークの形成によって特徴付けられる症状を予防的および治療的に処置する方法を開発する。 - 特許庁

The method for the labeling of β-amyloid plaque and neurofibrillary tangle in vivo and in vitro contains the contact of a compound of formula (I) with mammalian tissue.例文帳に追加

式（Ｉ）の化合物を哺乳動物組織と接触させることを含んで成る、βアミロイド斑及び神経原線維変化をインビボ及びインビトロで標識するための方法。 - 特許庁

To provide a compound that exhibits high bonding specificity to an amyloid β protein and high permeability through blood brain barriers as well as rapid disappearance from a region other than intracerebral senile plaque.例文帳に追加

アミロイドβタンパク質に対する高い結合特異性、高い血液脳関門の透過性、脳内老人斑以外の部位からの速やかな消失性を併せ持つ化合物を提供する。 - 特許庁

To provide a compound simultaneously having high binding specificity to amyloid β-protein, high capability of permeating through the blood-brain barrier and a high rate of disappearance from regions other than intracerebral senile plaque.例文帳に追加

アミロイドβ蛋白に対する高い結合特異性、高い血液脳関門の透過性、脳内老人斑以外の部位からの速やかな消失性を併せ持つ化合物を提供する。 - 特許庁

To provide a treating agent for Alzheimer's disease, inhibiting the formation of senile plaque and the storage of amyloid in central nervous system and without causing adverse effects such as encephalitis, a liver disorder, etc., and having a high safety.例文帳に追加

中枢神経系での老人斑の形成およびアミロイドの沈着を抑制し、かつ脳炎、肝障害などの副作用を起こさない、安全性の高いアルツハイマー病の治療剤の提供。 - 特許庁

To obtain a compound for graphic diagnosis probes of diseases in which amyloid β-protein is accumulated, and a composition and to provide a kit each containing the compound, a method for dyeing senile plaque, and to obtain a medicinal composition for preventing and treating diseases in which a protein β-sheet structure becomes a cause of disease.例文帳に追加

アミロイドβ蛋白が蓄積する疾患の画像診断プローブ用化合物、それを含有する組成物、キット、老人斑の染色方法、蛋白βシート構造が病因となる疾患予防、治療用医薬組成物の提供。 - 特許庁