cardioskeletalとは 意味・読み方・使い方

形容詞

cardioskeletal (not comparable)

1. (anatomy かつ physiology) Relating to the heart and the skeleton.
   • 2016, Hill Gallant, KM et al, “Nutrition in cardioskeletal health”, in Adv Nutr, volume 7, number 3, DOI:10.3945/an.115.011189, PMID 27184281, pages 544-555:

     Bone and heart health are linked through a variety of cellular, endocrine, and metabolic mechanisms, including the bidirectional effects of mineral-regulating hormones parathyroid hormone and fibroblast growth factor 23. Nutrition plays an important role in the development of both cardiovascular and bone disease.

2. (anatomy かつ physiology) Relating to both cardiac muscle and skeletal muscle, two types of striated muscle (in various animals including humans) that can both be affected by, for example, desminopathies or dystrophinopathies, causing myopathies of cardiac and skeletal muscle tissue.
   • 2004, Kaminska, A et al, “Small deletions disturb desmin architecture leading to breakdown of muscle cells and development of skeletal or cardioskeletal myopathy”, in Hum Genet, volume 114, number 3, DOI:10.1007/s00439-003-1057-7, PMID 14648196, pages 306-313:

     Desmin (DES) mutations have been recognized as a cause of desmin-related myopathy (OMIM 601419), or desminopathy, a disease characterized by progressive limb muscle weakness and accumulation of desmin-reactive granular aggregates in the myofibers. We have studied three families with skeletal or cardioskeletal myopathy caused by small in-frame deletions in the desmin gene.