| fly | 遺伝子名 | alkB |
| 同義語(エイリアス) | AlkB; BEST:LD02396; CG33250 | |
| SWISS-PROTのID | --- | |
| EntrezGeneのID | EntrezGene:2768870 | |
| その他のDBのID | FlyBase:FBgn0065035 |
| human | 遺伝子名 | alkB |
| 同義語(エイリアス) | ALKBH1; ALKBH; hABH; Alkylated DNA repair protein alkB homolog 1; ABH; alkB, alkylation repair homolog 1 (E. coli) | |
| SWISS-PROTのID | SWISS-PROT:Q13686 | |
| EntrezGeneのID | EntrezGene:8846 | |
| その他のDBのID | HGNC:17911 |
| mouse | 遺伝子名 | alkB |
| 同義語(エイリアス) | Alkbh; 2700073G19Rik; hABH; Alkbh1; alkB, alkylation repair homolog 1 (E. coli) | |
| SWISS-PROTのID | --- | |
| EntrezGeneのID | EntrezGene:211064 | |
| その他のDBのID | MGI:2384034 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/07/27 13:09 UTC 版)
AlkB protein is a protein induced during an adaptive response and is involved in the direct reversal of alkylation damage . AlkB specifically removes alkylation damage to single stranded (SS) DNA caused by SN2 type of chemical agents . It efficiently removes methyl groups from 1-methyl adenines, 3-methyl cytosines in SS DNA . AlkB belongs to the Fe (II)/2-oxoglutarate-dependent dioxygenase superfamily and oxidatively demethylates the DNA substrate . Demethylation by AlkB is accompanied with release of CO2, succinate and formaldehyde .