出典:Wiktionary
出典:Wikipedia
出典:『Wikipedia』 (2011/06/12 06:43 UTC 版)
Anaphase-Promoting Complex (APC), also called cyclosome, is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome. The APC is a large complex of 11–13 subunit proteins, including a cullin (Apc2) and RING (Apc11) subunit much like SCF. Other parts of the APC still have unknown functions, but are highly conserved.