| human | 遺伝子名 | CYP2D6 |
| 同義語(エイリアス) | P450C2D; Debrisoquine 4-hydroxylase; MGC120389; MGC120390; Cytochrome P450 2D6; CYP2D; CPD6; CYP2DL1; P450-DB1; CYP2D@; CYPIID6 | |
| SWISS-PROTのID | SWISS-PROT:P10635 | |
| EntrezGeneのID | EntrezGene:1565 | |
| その他のDBのID | HGNC:2625 |
| rat | 遺伝子名 | Cyp2d6 |
| 同義語(エイリアス) | cytochrome P450 subfamily 2D polypeptide 6; Cytochrome P450 subfamily IID polypeptide 6; Cyp2d6_mapped | |
| SWISS-PROTのID | --- | |
| EntrezGeneのID | EntrezGene:170518 | |
| その他のDBのID | RGD:68939 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/07/11 08:35 UTC 版)
Cytochrome P450 2D6 (CYP2D6), a member of the cytochrome P450 mixed-function oxidase system, is one of the most important enzymes involved in the metabolism of xenobiotics in the body. Also, many substances are bioactivated by CYP2D6 to form their active compounds. While CYP2D6 is involved in the oxidation of a wide range of substrates of all the CYPs, there is considerable variability in its expression in the liver. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.