出典:Wikipedia
出典:『Wikipedia』 (2011/06/17 08:00 UTC 版)
MALAT 1 (metastasis associated lung adenocarcinoma transcript 1) is also known as NEAT2 (noncoding nuclear-enriched abundant transcript 2). It is a large, infrequently spliced non-coding RNA, which is highly conserved amongst mammals. It is highly expressed in the nucleus. It is associated with metastasis, and positively regulates cell motility via the transcriptional and/or post-transcriptional regulation of motility-related genes.