human | 遺伝子名 | nuclear receptor coactivator 1 |
同義語(エイリアス) | RIP160; Steroid receptor coactivator 1; NY-REN-52 antigen; MGC129720; Nuclear receptor coactivator 1; NCOA1; Protein Hin-2; NCoA-1; SRC1; SRC-1; F-SRC-1; MGC129719 | |
SWISS-PROTのID | SWISS-PROT:Q15788 | |
EntrezGeneのID | EntrezGene:8648 | |
その他のDBのID | HGNC:7668 |
mouse | 遺伝子名 | nuclear receptor coactivator 1 |
同義語(エイリアス) | Steroid receptor coactivator 1; steroid receptor coactivator-1; SRC-a/NCoA-1; Nuclear receptor coactivator 1; NCoA-1; Ncoa1; SRC-1; SRC1; mNRC-1; MGC90703; Nuclear receptor coactivator protein 1; Src1 | |
SWISS-PROTのID | SWISS-PROT:P70365 | |
EntrezGeneのID | EntrezGene:17977 | |
その他のDBのID | MGI:1276523 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/03/12 11:05 UTC 版)
The nuclear receptor coactivator 1 (NCOA1) is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity (EC 2.3.1.48). NCOA1 is recruited to DNA promotion sites by ligand-activated nuclear receptors. NCOA1, in turn, acylates histones, which makes downsteam DNA more accessible to transcription. Hence, NCOA1 assists nuclear receptors in the upregulation of DNA expression.