| fission_yeast | 遺伝子名 | pin1 |
| 同義語(エイリアス) | SPCC16C4.03; Peptidyl-prolyl cis-trans isomerase pin1; peptidyl-prolyl cis-trans isomerase Pin1 | |
| SWISS-PROTのID | SWISS-PROT:O74448 | |
| EntrezGeneのID | --- | |
| その他のDBのID | GeneDB_SPombe:SPCC16C4.03 |
| fly | 遺伝子名 | Pin1 |
| 同義語(エイリアス) | CG17051; dod; Protein dodo; dodo | |
| SWISS-PROTのID | SWISS-PROT:P54353 | |
| EntrezGeneのID | EntrezGene:33111 | |
| その他のDBのID | FlyBase:FBgn0015379 |
| human | 遺伝子名 | PIN1 |
| 同義語(エイリアス) | Rotamase Pin1; PPIase Pin1; DOD; UBL5 | |
| SWISS-PROTのID | SWISS-PROT:Q13526 | |
| EntrezGeneのID | EntrezGene:5300 | |
| その他のDBのID | HGNC:8988 |
| human | 遺伝子名 | PIN1 |
| 同義語(エイリアス) | Activated in prostate cancer protein; PDZD2; KIAA0300; AIPC; PAPIN; PDZ domain containing 3; PDZK3; PDZ domain-containing protein 2; PDZ domain containing 2; PDZ domain-containing protein 3 | |
| SWISS-PROTのID | SWISS-PROT:O15018 | |
| EntrezGeneのID | EntrezGene:23037 | |
| その他のDBのID | HGNC:18486 |
| mouse | 遺伝子名 | Pin1 |
| 同義語(エイリアス) | 0610025L01Rik; Rotamase Pin1; D9Bwg1161e; PPIase Pin1 | |
| SWISS-PROTのID | SWISS-PROT:Q9QUR7 | |
| EntrezGeneのID | EntrezGene:23988 | |
| その他のDBのID | MGI:1346036 |
| rat | 遺伝子名 | Pin1 |
| 同義語(エイリアス) | Papin; Pdzk3; PDZ domain-containing protein 2; Pdzd2; PDZ domain-containing protein 3; PDZ domain containing 3 | |
| SWISS-PROTのID | SWISS-PROT:Q9QZR8 | |
| EntrezGeneのID | EntrezGene:65034 | |
| その他のDBのID | RGD:619958 |
| yeast | 遺伝子名 | PIN1 |
| 同義語(エイリアス) | PTF1; YJR017C; J1452; PPIase ESS1; Peptidyl-prolyl cis-trans isomerase ESS1; Parvulin ESS1; ESS1; Processing/termination factor 1 | |
| SWISS-PROTのID | SWISS-PROT:P22696 | |
| EntrezGeneのID | EntrezGene:853475 | |
| その他のDBのID | SGD:S000003778 |
| zfish | 遺伝子名 | pin1 |
| 同義語(エイリアス) | zgc:73206; MGC73206 | |
| SWISS-PROTのID | --- | |
| EntrezGeneのID | EntrezGene:393721 | |
| その他のDBのID | ZFIN:ZDB-GENE-040426-1714 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/01/22 17:03 UTC 版)
Pin 1, or peptidyl-prolyl cis/trans isomerase (PPIase), isomerizes only phospho-Serine/Threonine-Proline motifs. The enzyme binds to a subset of proteins and thus plays a role as a post phosphorylation control in regulating protein function. Studies have shown that the deregulation of Pin1 may play a pivotal role in various diseases. Notably, the up-regulation of Pin1 may be implicated in certain cancers, and the down-regulation of Pin1 may be implicated in Alzheimer's disease. Inhibitors of Pin1 may have therapeutic implications for cancer and immune disorders.