TrpV6とは 意味・読み方・使い方

TRPV6 is a membrane calcium channel which is responsible for the first step in calcium absorption in the intestine. It was first named CAT1 , or ECaC2, and has been described in the intestine in several species, including humans . It is located in the apical brush-border membrane of the intestinal enterocyte where is regulates calcium entry into the cell. It is most abundant in the proximal small intestine (duodenum and jejunum) where calbindin and the calcium-pumping ATPase are also found. The TRPV6 calcium transporter also found in the human placenta, pancreas and prostate gland and in some species in the kidney where the related channel TRPV5 is strongly expressed.