〈断念する〉 give up (as hopeless); abandon; 【形式ばった表現】 forsake
〈事業などに〉 wash one's hands of
starting a train before all the passengers are on board
〈比喩的〉 starting an action without considering objections to it any longer; 《make》 a snap decision
読み方 みきり
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(=果断)decision; resolution