| human | 遺伝子名 | CARM1 |
| 同義語(エイリアス) | Histone-arginine methyltransferase CARM1; Protein arginine N-methyltransferase 4; PRMT4 | |
| SWISS-PROTのID | SWISS-PROT:Q86X55 | |
| EntrezGeneのID | EntrezGene:10498 | |
| その他のDBのID | HGNC:23393 |
| mouse | 遺伝子名 | Carm1 |
| 同義語(エイリアス) | Histone-arginine methyltransferase CARM1; Protein arginine N-methyltransferase 4; MGC46828; Prmt4 | |
| SWISS-PROTのID | SWISS-PROT:Q9WVG6 | |
| EntrezGeneのID | EntrezGene:59035 | |
| その他のDBのID | MGI:1913208 |
| rat | 遺伝子名 | Carm1 |
| 同義語(エイリアス) | Histone-arginine methyltransferase CARM1; protein arginine N-methyltransferase 4; Protein arginine N-methyltransferase 4; Prmt4 | |
| SWISS-PROTのID | SWISS-PROT:Q4AE70 | |
| EntrezGeneのID | EntrezGene:363026 | |
| その他のDBのID | RGD:1305879 |
| zfish | 遺伝子名 | carm1 |
| 同義語(エイリアス) | Histone-arginine methyltransferase CARM1; si:dkey-204f11.63; Protein arginine N-methyltransferase 4; PRMT4; zgc:100805 | |
| SWISS-PROTのID | SWISS-PROT:Q6DC04 | |
| EntrezGeneのID | EntrezGene:445251 | |
| その他のDBのID | ZFIN:ZDB-GENE-040724-77 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/04/14 01:59 UTC 版)
CARM1 (coactivator-associated arginine methyltransferase 1) is an enzyme (EC 2.1.1.125) encoded by the CARM1 gene found in human beings, as well as many other mammals. It has a polypeptide (L) chain type that is 348 resdidues long, and is made up of alpha helices and beta sheets. Its main function includes catalyzing the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. CARM1 is a secondary coactivator through its association with p160 family (SRC-1, GRIP1, AIB) of coactivators. It is responsible for moving cells toward the inner cell mass in developing blastocysts. This gene also plays an important role in androgen receptors and may play a role in prostate cancer progression.