the active ingredient in a drug used to lower the amount of cholesterol in the blood and to prevent stroke and heart attack. it is also being studied in the treatment of cancer and other conditions. pravastatin blocks an enzyme that helps make cholesterol in the body. it may also make tumor cells more sensitive to anticancer drugs. it is a type of hmg-coa reductase inhibitor, a type of statin, and a type of chemosensitizer.
出典:Wiktionary
出典:『Wiktionary』 (2025/11/02 21:41 UTC 版)
From pra- (of unknown origin) + -vastatin (“HMG CoA reductase inhibitor”).
(This etymology is missing or incomplete. Please add to it, or discuss it at the Etymology scriptorium.)
pravastatin (uncountable)
出典:Wikipedia
出典:『Wikipedia』 (2011/02/01 13:52 UTC 版)
Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used for lowering cholesterol and preventing cardiovascular disease. Initially known as CS-514, it was originally identified in a bacterium called Nocardia autotrophica by researchers of the Sankyo Pharma Inc.. It is presently being marketed outside Japan by the pharmaceutical company Bristol-Myers Squibb.