a type of virus used in cancer therapy. the virus is changed in the laboratory and cannot cause disease. viral vectors may produce tumor antigens (proteins found on a tumor cell) to stimulate an antitumor immune response in the body. viral vectors may also be used to carry genes that can change cancer cells back to normal cells.
出典:Wikipedia
出典:『Wikipedia』 (2011/05/19 06:35 UTC 版)
Viral vectors are a tool commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism (in vivo) or in cell culture (in vitro). Viruses have evolved specialized molecular mechanisms to efficiently transport their genomes inside the cells they infect. Delivery of genes by a virus is termed transduction and the infected cells are described as transduced. Molecular biologists first harnessed this machinery in the 1970s. Paul Berg used a modified SV40 virus containing DNA from the bacteriophage lambda to infect monkey kidney cells maintained in culture.