| human | 遺伝子名 | CXCL16 |
| 同義語(エイリアス) | Transmembrane chemokine CXCL16; UNQ2759/PRO6714; SRPSOX; chemokine (C-X-C motif) ligand 16; CXCLG16; SR-PSOX; Small inducible cytokine B16 precursor; SCYB16 | |
| SWISS-PROTのID | SWISS-PROT:Q9H2A7 | |
| EntrezGeneのID | EntrezGene:58191 | |
| その他のDBのID | HGNC:16642 |
| mouse | 遺伝子名 | Cxcl16 |
| 同義語(エイリアス) | 0910001K24Rik; Transmembrane chemokine CXCL16; Scavenger Receptor; chemokine (C-X-C motif) ligand 16; SR-PSOX; Srpsox; AV290116; SR-PSOX/CXCL16; Small inducible cytokine B16 precursor; BB024863 | |
| SWISS-PROTのID | SWISS-PROT:Q8BSU2 | |
| EntrezGeneのID | EntrezGene:66102 | |
| その他のDBのID | MGI:1932682 |
| rat | 遺伝子名 | Cxcl16 |
| 同義語(エイリアス) | ||
| SWISS-PROTのID | --- | |
| EntrezGeneのID | EntrezGene:497942 | |
| その他のDBのID | RGD:1562928 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2010/07/22 16:40 UTC 版)
Chemokine (C-X-C motif) ligand 16 (CXCL16) is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids), CXCL16 is composed of a CXC chemokine domain, a mucin-like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2. These are unusual features for a chemokine, and allow CXCL16 to be expressed as a cell surface bound molecule, as well as a soluble chemokine. CXCL16 is produced by dendritic cells found in the T cell zones of lymphoid organs, and by cells found in the red pulp of the spleen. Cells that bind and migrate in response to CXCL16 include several subsets of T cells, and natural killer T (NKT) cells. CXCL16 interacts with the chemokine receptor CXCR6, also known as Bonzo. Expression of CXCL16 is induced by the inflammatory cytokines IFN-gamma and TNF-alpha. The gene for human CXCL16 is located on chromosome 17.