細胞依存性抗体の英語

従来の抗体と比較して高いＡＤＣＣ（抗体依存性細胞障害）活性およびＣＤＣ（補体依存性細胞障害）活性を有する抗グリピカン３抗体、ならびにかかる抗体を有効成分とする細胞増殖抑制剤及び抗癌剤の提供。例文帳に追加

To provide an anti-glypican 3 antibody having higher ADCC (antibody-dependent cellular cytotoxicity) activity and CDC (complement-dependent cytotoxicity) activity compared with those of conventional antibody, and provide a cell growth inhibitor and an anticancer agent containing the antibody as an active component. - 特許庁

種々の疾患に有用な抗体依存性細胞障害活性の高い、抗体、抗体の断片、抗体のＦｃ領域を有する融合タンパク質等の抗体組成物の製造に用いる細胞、該細胞を用いた抗体組成物の製造方法、抗体組成物、およびそれらの用途を提供する。例文帳に追加

To provide an antibody having high antibody-dependent cellular cytotoxic activity and useful for various diseases, a fragment of the antibody, a cell used for producing an antibody composition such as a fusion protein having the Fc region of the antibody, a method for producing the antibody composition using the cell, the antibody composition and use thereof. - 特許庁

メソテリン陽性細胞に特異的に結合し、当該細胞によって内在化し、また抗体依存性細胞障害活性等の免疫エフェクター活性を誘発する、モノクローナルおよびポリクローナル抗体。例文帳に追加

This invention relates to the use of monoclonal and polyclonal antibodies that specifically bind to and become internalized by mesothelin-positive cells and also induce immune effector activity such as antibody-dependent cellular cytotoxicity. - 特許庁

抗−CD20抗体依存性細胞介在性細胞溶解をCD20^+ 細胞に対して誘導し且つATCC寄託番号69119 のトランスフェクトーマにより生産されるキメラ抗体と実質的に同じＢ−細胞涸渇活性を有するキメラ抗CD20抗体、及びその利用。例文帳に追加

Used is a chimeric anti-CD20 antibody having substantially same B cell-consuming activity as that of a chimeric antibody which induces anti-CD20 antibody-dependent cell-mediated cytolysis to CD20^+ cells and is produced by transfectoma accorded ATCC Deposit No. 69119. - 特許庁

本発明は、種々の疾患に有用な抗体依存性細胞障害活性の高い抗体抗体のＦｃ領域を有する融合タンパク質等の抗体組成物のＡＤＣＣ活性を促進する方法に関する。例文帳に追加

There is provided the method for promoting ADCC activity of an antibody composition such as a fused protein having the Fc region of an antibody having high antibody-dependent cellular cytotoxic activity useful for various diseases. - 特許庁

上皮細胞成長因子受容体ファミリーに対する抗体、さらに、上皮細胞成長因子受容体ファミリーの異なる２つ以上の部位を認識する当該抗体を含有する、補体依存的殺細胞活性を有する、癌を治療するための医薬組成物。例文帳に追加

The antibody against the epidermal cell growth factor receptor family is disclosed together with the pharmaceutical composition for treating cancer, containing the antibody to recognize at least two different sites of the family and having complement-dependent cytotoxicity activity. - 特許庁

本発明は、種々の疾患に有用な抗体依存性細胞障害活性の高い抗体抗体のＦｃ領域を有する融合タンパク質等の抗体組成物の製造方法に関する。例文帳に追加

The method for producing an antibody composition such as a fused protein having the Fc domain of an antibody having high antibody-dependent cellular cytotoxic activity useful for various diseases is provided. - 特許庁

ヒトＬＡＴ１に結合でき、癌細胞に対して特異的に抗体依存性細胞障害を誘導する新規な抗体を有効成分として含有する、現在治療困難な固形腫瘍をはじめとした各種悪性腫瘍の予防または治療剤の提供。例文帳に追加

To provide a preventing or treating agent of various malignant tumors including solid tumors which are presently difficult to be treated, containing a new antibody binding with human LAT1 and specifically inducing an antibody-dependant cytotoxicity against cancer cells, as an active ingredient. - 特許庁