fly | 遺伝子名 | protein tyrosine phosphatase |
同義語(エイリアス) | Protein tyrosine phosphatase 61F; BEST:LP01280; PTP61F; ptp61F; Tyrosine-protein phosphatase non-receptor type 61F; CG9178; anon-WO0140519.98; dptp61F; DPTP61F; anon-WO0118547.297; R-PTP 61F; dPTP61F; protein-tyrosine-phosphatase; Ptp61F; CG9181 | |
SWISS-PROTのID | SWISS-PROT:Q9W0G1 | |
EntrezGeneのID | EntrezGene:38160 | |
その他のDBのID | FlyBase:FBgn0003138 |
rat | 遺伝子名 | protein-tyrosine phosphatase |
同義語(エイリアス) | PTP-1B; MGC93562; Protein-tyrosine phosphatase 1B; Tyrosine-protein phosphatase non-receptor type 1; Ptpn1; 11191; Ptp; protein tyrosine phosphatase, non-receptor type 1 | |
SWISS-PROTのID | SWISS-PROT:P20417 | |
EntrezGeneのID | EntrezGene:24697 | |
その他のDBのID | RGD:61965 |
worm | 遺伝子名 | protein-tyrosine-phosphatase |
同義語(エイリアス) | CE32051; WP:CE32052; F56D1.4c; F56D1.4b; CE32052; WP:CE32053; F56D1.4a; WP:CE32051; F56D1.4; CE32053; clr-1 | |
SWISS-PROTのID | --- | |
EntrezGeneのID | EntrezGene:3565419 | |
その他のDBのID | WormBase:WBGene00000548 |
worm | 遺伝子名 | protein-tyrosine-phosphatase |
同義語(エイリアス) | CE03501; M05D6.3; WP:CE03501 | |
SWISS-PROTのID | --- | |
EntrezGeneのID | EntrezGene:174355 | |
その他のDBのID | WormBase:WBGene00010876 |
yeast | 遺伝子名 | protein tyrosine phosphatase |
同義語(エイリアス) | YNL2480W; N2480; MSG5; YNL053W; Tyrosine-protein phosphatase MSG5 | |
SWISS-PROTのID | SWISS-PROT:P38590 | |
EntrezGeneのID | EntrezGene:855674 | |
その他のDBのID | SGD:S000004998 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/04/26 17:42 UTC 版)
Protein tyrosine phosphatases (PTPs) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Protein tyrosine (pTyr) phosphorylation is a common post-translational modification which can create novel recognition motifs for protein interactions and cellular localisation, affect protein stability, and regulate enzyme activity. Consequently, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases (PTPase; EC 3.1.3.48) catalyse the removal of a phosphate group attached to a tyrosine residue, using a cysteinyl-phosphate enzyme intermediate. These enzymes are key regulatory components in signal transduction pathways (such as the MAP kinase pathway) and cell cycle control, and are important in the control of cell growth, proliferation, differentiation and transformation.