fly | 遺伝子名 | caspase-1 |
同義語(エイリアス) | dcp-1; dcp1; Death caspase-1; CG5370; caspase; Caspase-1 precursor; l(2)01862; Dcp-1; l(2)02132; DCP-1 | |
SWISS-PROTのID | SWISS-PROT:O02002 | |
EntrezGeneのID | EntrezGene:37729 | |
その他のDBのID | FlyBase:FBgn0010501 |
mouse | 遺伝子名 | caspase 1 |
同義語(エイリアス) | Il1bc; Casp1; Interleukin-1 beta convertase; interleukin 1 beta-converting enzyme; IL-1BC; Interleukin-1 beta-converting enzyme; Caspase-1; Caspase-1 precursor; p45; IL-1 beta-converting enzyme; CASP-1; ICE | |
SWISS-PROTのID | SWISS-PROT:P29452 | |
EntrezGeneのID | EntrezGene:12362 | |
その他のDBのID | MGI:96544 |
rat | 遺伝子名 | caspase 1 |
同義語(エイリアス) | Il1bc; Casp1; Interleukin-1 beta convertase; Ice; IL-1BC; Interleukin-1 beta-converting enzyme; Il1bce; Caspase-1 precursor; interleukin 1beta converting enzyme; p45; IL-1 beta-converting enzyme; interleukin 1 beta convertase; CASP-1; ICE | |
SWISS-PROTのID | SWISS-PROT:P43527 | |
EntrezGeneのID | EntrezGene:25166 | |
その他のDBのID | RGD:2274 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/04/08 09:20 UTC 版)
Caspase 1 is an enzyme that proteolytically cleaves other proteins, such as the precursor forms of the inflammatory cytokines interleukin 1-β and interleukin 18, into active mature peptides. It belongs to a family of cysteine proteases known as caspases that always cleave proteins following an aspartic acid residue. Caspase 1 is produced as a zymogen that is cleaved into 20 kDa (p20) and 10 kDa (p10) subunits that become part of the active enzyme. Active caspase 1 contains two heterodimers of p20 and p10. It interacts with another CARD domain containing protein called PYCARD (or ASC) and is involved in inflammasome formation and activation of inflammatory processes.