human hepatocytesとは 意味・読み方・使い方

To provide a method for obtaining a mouse individual of which the mouse hepatocytes are substituted by human hepatocytes grown from human adult hepatocytes in a high ratio, and to provide a method for improving fatty liver of a mouse to which human young hepatocytes are transplanted and which suffers from immunodeficiency hepatopathy.例文帳に追加

成人肝細胞から増殖したヒト肝細胞が高い割合でマウス肝細胞に置換したマウス個体を得る方法、および若年ヒト肝細胞を移植した免疫不全肝障害マウスの脂肪肝を改善する方法を提供する。 - 特許庁

The hemophilia B curative agent contains human hepatocytes proliferated in the body of an immunodeficient nonhuman animal with hepatopathy.例文帳に追加

免疫不全肝障害非ヒト動物体内で増殖したヒト肝細胞を含む、血友病B治療剤。 - 特許庁

In this method for obtaining the mouse individual, the human adult hepatocytes are transplanted to a mouse suffering from the immunodeficiency hepatopathy and then a human growth hormone is administered to the mouse, so that the substitution ratio of the human adult hepatocytes is increased twice or more.例文帳に追加

免疫不全肝障害マウスに成人肝細胞を移植し、このマウスにヒト成長ホルモンを投与することによって、成人肝細胞の置換率を約２倍以上に増加させる。 - 特許庁

To provide modified methods of producing human hepatocyte-like cells which exhibit phenotypes more similar to those of human hepatocytes, to provide the human hepatocyte-like cells, and to provide uses thereof.例文帳に追加

従来のシステムの改変により、ヒト肝細胞の表現型にさらに近いヒト肝細胞様細胞を製造すること。 - 特許庁

The hepatitis B virus-infected model cell is obtained by a method including: a first step of producing a chimera non-human animal by transplanting human hepatocytes to a non-human animal with an immunodeficient hepatopathy; a second step of separating human hepatocytes grown in the body of the chimera non-human animal; and a third step of infecting the separated human hepatocytes with the HBV.例文帳に追加

免疫不全肝障害非ヒト動物にヒト肝細胞を移植してキメラ非ヒト動物を作製する第１工程と、キメラ非ヒト動物体内で増殖したヒト肝細胞を分離する第２工程と、分離したヒト肝細胞にHBVを感染させる第３工程とを含む方法により得られるB型肝炎ウィルス感染モデル細胞。 - 特許庁

The human hepatocytes thus retrieved has the hemostatic function for coagulation factor IX-deleted human plasma.例文帳に追加

キメラ動物体内で増殖したヒト肝細胞は、凝固第IX因子を欠損するヒト血漿の止血機能を有する。 - 特許庁

The method for producing the hemophilia B curative agent in large quantities comprises the step of creating a chimeric nonhuman animal by transplanting human hepatocytes into an immunodeficient nonhuman animal with hepatopathy and the step of retrieving human hepatocytes proliferated in the body of the chimeric nonhuman animal.例文帳に追加

免疫不全肝障害非ヒト動物にヒト肝細胞を移植してキメラ非ヒト動物を作製する工程と、キメラ非ヒト動物体内で増殖したヒト肝細胞を回収する工程とを含む、血友病B治療剤の大量製造方法。 - 特許庁