misfoldとは 意味・読み方・使い方

語源

From mis- +‎ fold.

発音

• (verb) IPA: /mɪsˈfoʊld/
• (noun) IPA: /ˈmɪsfoʊld/
• 韻: -əʊld

動詞

misfold (third-person singular simple present misfolds, present participle misfolding, simple past and past participle misfolded)

1. (biochemistry, intransitive, of a protein or nucleic acid) To fold into an unusual or incorrect tertiary structure; misfolded proteins occur in various diseases, including amyloidoses and dementias, although the question of causation versus consequence is not yet definitively answered for dementias.
   • 2021 March 1, Anderson, K.N., Overcast, W.B., Brosch, J.R., Graner, B.D., Veronesi, M.C., “Prionopathies and Prionlike Protein Aberrations in Neurodegenerative Diseases”, in American Society of Neuroradiology, volume 11, number 2, →DOI, pages 127-148:

     The prionopathies are best known among the neurodegenerative diseases for their ability to misfold, self-propagate, and infect other organisms.

名詞

misfold (plural misfolds)

1. An incorrect or abnormal folding.