PDQ®がん用語辞書 英語版
methylnaltrexone
- 原文
the active ingredient in a drug used to relieve certain side effects caused by treatment with opiods (pain killers similar to morphine), such as constipation (hard, dry stools), itching, and low urine flow. methylnaltrexone binds to opioid receptors outside the brain and may block the side effects of opioid drugs without affecting their ability to relieve pain. methylnaltrexone is a type of peripheral opioid receptor antagonist.
調べた例文を記録して、効率よく覚えましょう
Weblio会員無料で登録できます
履歴機能
過去に調べた単語を確認できる
語彙力診断
診断回数が4回に増加
マイ単語帳
便利な学習機能付き
マイ例文帳
文章で意味を理解できる
ライフサイエンス辞書
methylnaltrexone
関連語
- 同義語（異表記）
- 17-(cyclopropylmethyl)-4,5-epoxy
-3,14-dihydroxymorphinanium-6-onemethyl-naltrexone hydrobromidemethylnaltrexoneMRZ 2663BRMRZ-2663naltrexone methobromidenaltrexonium methiodideレリストール
Wiktionary英語版
出典：Wiktionary
methylnaltrexone
語源
From methyl + naltrexone.
名詞
methylnaltrexone (uncountable)
- (pharmacology) A peripherally-acting μ-opioid antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals.
- 2008 January 26, Bloomberg News, “Wyeth Says It May Cut 10% of Jobs”, in New York Times[1]:
- Since Jan. 1, 2007, the Food and Drug Administration has postponed clearance of Wyeth’s bifeprunox for schizophrenia, Pristiq for depression and menopausal hot flashes, Viviant for bone loss and methylnaltrexone for constipation.
ウィキペディア英語版
出典：Wikipedia
Methylnaltrexone
出典:『Wikipedia』 (2011/05/18 15:55 UTC 版)
英語による解説
ウィキペディア英語版からの引用
- 引用
Methylnaltrexone (MNTX, trade name Relistor) is one of the newer agents of peripherally-acting μ-opioid antagonists that act to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals. Because it contains a permanently charged tetravalent nitrogen atom, it cannot cross the blood-brain barrier, and so has antagonist effects throughout the body, counteracting effects such as itching and constipation, but without affecting opioid effects in the brain such as analgesia. However, since a significant fraction (up to 60 %) of opioid analgesia can be mediated by opioid receptors on peripheral sensory neurons, particularly in inflammatory conditions such as arthritis, traumatic or surgical pain, MNTX may increase pain under such circumstances.
- Copyright ©2004-2026 Translational Research Informatics Center. All Rights Reserved.
財団法人先端医療振興財団 臨床研究情報センター
- Copyright (C) 2026 ライフサイエンス辞書プロジェクト
- Wiktionary
- Text is available under Creative Commons Attribution-ShareAlike (CC-BY-SA) and/or GNU Free Documentation License (GFDL).
Weblio英和・和英辞典に掲載されている「Wiktionary英語版」の記事は、Wiktionaryのmethylnaltrexone (改訂履歴)の記事を複製、再配布したものにあたり、Creative Commons Attribution-ShareAlike (CC-BY-SA)もしくはGNU Free Documentation Licenseというライセンスの下で提供されています。
- Wikipedia
- Text is available under Creative Commons Attribution-ShareAlike (CC-BY-SA) and/or GNU Free Documentation License (GFDL).
Weblio英和・和英辞典に掲載されている「Wikipedia英語版」の記事は、WikipediaのMethylnaltrexone (改訂履歴)の記事を複製、再配布したものにあたり、Creative Commons Attribution-ShareAlike (CC-BY-SA)もしくはGNU Free Documentation Licenseというライセンスの下で提供されています。
