one of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of oxygen or glucose (sugar). heat-shock proteins help other proteins function in normal cells and may be present at high levels in cancer cells. blocking the activity of a heat-shock protein called hsp90 is being studied in the treatment of cancer. other heat-shock proteins including hsp70 and gp96 are being studied in vaccines to treat cancer. also called hsp and stress protein.
rat | 遺伝子名 | heat shock protein |
同義語(エイリアス) | Selk; Selenoprotein K | |
SWISS-PROTのID | SWISS-PROT:P59798 | |
EntrezGeneのID | EntrezGene:290549 | |
その他のDBのID | RGD:1303129 |
yeast | 遺伝子名 | heat shock protein |
同義語(エイリアス) | Protein with internal repeats 2; YJL159W; 150 kDa heat shock glycoprotein precursor; PIR2; CCW7; J0558; HSP150; Covalently-linked cell wall protein 7; secretory glycoprotein; ORE1 | |
SWISS-PROTのID | SWISS-PROT:P32478 | |
EntrezGeneのID | EntrezGene:853281 | |
その他のDBのID | SGD:S000003695 |
yeast | 遺伝子名 | heat shock protein |
同義語(エイリアス) | Mitochondrial protein import protein MAS5; N2418; YDJ1; YNL064C; MAS5; Yeast dnaJ protein 1; HSP40; YNL2418C | |
SWISS-PROTのID | SWISS-PROT:P25491 | |
EntrezGeneのID | EntrezGene:855661 | |
その他のDBのID | SGD:S000005008 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/07/15 02:00 UTC 版)
Heat shock proteins (HSP) are a class of functionally related proteins whose expression is increased when cells are exposed to elevated temperatures or other stress. This increase in expression is transcriptionally regulated. The dramatic upregulation of the heat shock proteins is a key part of the heat shock response and is induced primarily by heat shock factor (HSF). HSPs are found in virtually all living organisms, from bacteria to humans.