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遺伝子名称シソーラス
PKC-alpha
| human | 遺伝子名 | PKC-alpha |
| 同義語（エイリアス） | PKCA; PKC-A; protein kinase C, alpha; Protein kinase C alpha type; MGC129901; AAG6; MGC129900; PRKCA; PRKACA | |
| SWISS-PROTのID | SWISS-PROT:P17252 | |
| EntrezGeneのID | EntrezGene:5578 | |
| その他のDBのID | HGNC:9393 |
| mouse | 遺伝子名 | PKC-alpha |
| 同義語（エイリアス） | PKC-A; protein kinase C, alpha; Pkca; Protein kinase C alpha type; Prkca | |
| SWISS-PROTのID | SWISS-PROT:P20444 | |
| EntrezGeneのID | EntrezGene:18750 | |
| その他のDBのID | MGI:97595 |
| rat | 遺伝子名 | PKC-alpha |
| 同義語（エイリアス） | PKC-A; Pkca; protein kinase C, alpha; Protein kinase C alpha type; Prkca | |
| SWISS-PROTのID | SWISS-PROT:P05696 | |
| EntrezGeneのID | EntrezGene:24680 | |
| その他のDBのID | RGD:3395 |
本文中に表示されているデータベースの説明
ウィキペディア英語版
出典：Wikipedia
PKC alpha
出典:『Wikipedia』 (2011/04/14 23:49 UTC 版)
英語による解説
ウィキペディア英語版からの引用
- 引用
Protein kinase C alpha (PKCα), also known as PRKCA, refers to both a human gene and the protein that is encoded by it. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca2+ handling in myocytes.
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