英和和英

to experience difficulties

to cause a person to experience difficulties

to give one trouble

to drain the cup of bitterness to the dregs

the act of going though a lot of trouble

hardships

without taking pains

to go through all sorts of hardships―drain the bitter cup to the dregs

to experience many hardships

of a person, having taken great effort to do something

overcare―over-anxiety―over-concern―over-solicitude

He has drained the cup of sorrow to the dregs.

Do not run to meet your trouble!

without troubling oneself

Do not meet trouble half-way

to meet trouble half-way―run to meet one's trouble

obtain with difficulty

a load of care

the stern realities of life―the grim realities of life

Care bows one down.

give pain or trouble to

working hard

Do not run to meet your trouble

to banish care

to thank a person for his or her efforts

a source of trouble

having secret trouble

a very difficult situation to cope with

with difficulty