英和和英

to give one trouble

to drain the cup of bitterness to the dregs

hardships

of a person, having taken great effort to do something

a load of care

to experience difficulties

the stern realities of life―the grim realities of life

to experience many hardships

Care is a foe to life.

Troubles are the lot of man.

to thank a person for his or her efforts

to cause a person to experience difficulties

to banish care

without troubling oneself

Troubles are the lot of man.

to go through all sorts of hardships―drain the bitter cup to the dregs

He has drained the cup of sorrow to the dregs.

a source of trouble

Do not run to meet your trouble!

the act of going though a lot of trouble

Care bows one down.

a result of one's effort

without taking pains

a very difficult situation to cope with

overcare―over-anxiety―over-concern―over-solicitude

“Care preys upon the mind.”【イディオム・格言的】

Care preys on the mind.

Care shortens life

to sow the seeds of future trouble

Banish care!