HMGB1とは 意味・読み方・使い方

This invention relates to a monoclonal antibody or antigen-binding fragment, wherein the binding thereof to a peptide consisting of specific amino acid residues 61 to 78, can be inhibited by 6E6 HMGB1 mAb.例文帳に追加

特定のアミノ酸残基61〜78からなるペプチドへの結合が6E6 HMGB1 mAbによって阻害され得る、単離されたモノクローナル抗体または抗原結合断片。 - 特許庁

The atheroma arteriosclerosis inhibitor includes a HMGB1 monoclonal antibody combined with a C tail of HMGB1 (High Mobility Group Box 1, B box 1 of a high migration rate group protein) as an active ingredient.例文帳に追加

ＨＭＧＢ１（High Mobility Group Box 1、高移動度群タンパク質のＢボックス１）のＣテイルに結合する抗ＨＭＧＢ１モノクローナル抗体を有効成分とするアテローム動脈硬化抑制剤。 - 特許庁

To clarify a combination of antibodies allowing the measurement of HMGB1 in a short time, e.g. a combination of HMGB1 antibodies, and to provide an immunological measuring method and an immunological measuring kit.例文帳に追加

短時間にＨＭＧＢ１の測定が可能な抗体、例えばＨＭＧＢ１抗体の組み合わせを明らかにし、免疫学的測定方法及び免疫学的測定キットを提供する。 - 特許庁

To provide an adsorbent material with such characteristics that HMGB1 in the body fluid is highly efficiently adsorbed and removed, and that blood cells such as leukocytes and thrombocytes necessary for the vital reaction are not removed.例文帳に追加

体液中のＨＭＧＢ１を高い効率で吸着除去し、かつ白血球、血小板などの生体反応に必要な血液細胞は除去しない性質を持つ吸着材。 - 特許庁

The body fluid purifying adsorbent material is characterized by an adsorbent body with anionic functional groups immobilized to a water-insoluble carrier which highly efficiently adsorbs HMGB1 in the body fluid, but does not substantially adsorb at least either leukocytes or thrombocytes.例文帳に追加

アニオン性の官能基が水不溶性担体に固定化されてなるＨＭＧＢ１の吸着体で、体液中のＨＭＧＢ１を高い効率で吸着し、かつ白血球または血小板の少なくともいずれかを実質的に吸着しないことを特徴とする体液浄化用吸着材。 - 特許庁