| fly | 遺伝子名 | patched |
| 同義語(エイリアス) | pat; Ptc; tuf; l(2)k02507; Ptc_Dm; Protein patched; rubr; tufted; rubberneck; Conf; BcDNA:RH36596; ptc; PTC; tuf: tufted; CG2411; Confused; Hedgehog receptor; patch | |
| SWISS-PROTのID | SWISS-PROT:P18502 | |
| EntrezGeneのID | EntrezGene:35851 | |
| その他のDBのID | FlyBase:FBgn0003892 |
| fly | 遺伝子名 | patched |
| 同義語(エイリアス) | patch | |
| SWISS-PROTのID | --- | |
| EntrezGeneのID | EntrezGene:252317 | |
| その他のDBのID | FlyBase:FBgn0003039 |
本文中に表示されているデータベースの説明
出典:Wiktionary
出典:Wikipedia
出典:『Wikipedia』 (2011/03/20 13:59 UTC 版)
Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. The original mutations in the ptc gene were discovered in the fruit fly Drosophila melanogaster by 1995 Nobel Laureates Eric F. Wieschaus and Christiane Nusslein-Volhard and colleagues, and the gene was independently cloned in 1989 by Joan Hooper in the laboratory of Matthew P. Scott, and by Philip Ingham and colleagues. Patched is an embryo-lethal segment polarity gene that is important for proper segmentation in the fly embryo. Patched controls the spatial distribution of Hedgehog protein in part via endocytosis of bound hedgehog protein, which is then targeted for lysosomal degradation.
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「patched」は動詞「patch」の過去形、または過去分詞です