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Wiktionary英語版での「Dickkopf」の意味 |
dickkopf
語源
Borrowed from German Dickkopf (“stubborn person”, literally “large head”), from the fact that Dickkopf-related protein 1 (DKK1), one of the dickkopf proteins, was found to be required for head formation in embryos. The word was coined by Andrei Glinka, Wei Wu, Hajo Delius, A. Paula Monaghan, Claudia Blumenstock, and Christof Niehrs in a 1998 article published in Nature:[1] see the quotation.
発音
名詞
dickkopf (複数形 dickkopfs)
- (biochemistry) Any of a family of glycoproteins that is involved in the development of the embryo. [from 1998]
- 2015 December 22, Kathryn L. McCabe [et al.], “Efficient Generation of Human Embryonic Stem Cell-derived Corneal Endothelial Cells by Directed Differentiation”, in PLOS ONE, volume 10, number 12, San Francisco, Calif.: PLOS, DOI: , ISSN 1932-6203, OCLC 70662135, article number e0145266:
- Some of the factors tested included: angiopoietin like protein 7 (ANGLPT7), epidermal growth factor (EGF), fibroblast growth factor 2 (FGF2), transforming growth factor beta 2 (TGF β 2), platelet derived growth factor b (PDGFB), and dickkopf related protein 2 (DKK2).
- 2016, Joseph G. Sinkovics, “Eukaryotic Single Cells and the First Cell Communities Then and Now”, in RNA/DNA and Cancer, Cham, Switzerland: Springer, DOI: , →ISBN, page 81:
参照
- ^ Michael H. Kagey; Xi He (December 2017), “Rationale for Targeting the Wnt Signalling Modulator Dickkopf-1 for Oncology”, in British Journal of Pharmacology, volume 174, issue 24, London: Wiley-Blackwell for the British Pharmacological Society, DOI: , ISSN 0007-1188, OCLC 1167996437: “DKK1 was originally identified in Xenopus as an inhibitor of β‐catenin‐dependent Wnt signalling and an inducer of head formation during embryogenesis, a phenotype that coined the Dickkopf (German for ‘big head, stubborn’) nomenclature (Glinka et al., 1998).”
1
MGC129562
遺伝子名称
2
MGC129563
遺伝子名称
3
UNQ258/PRO295
遺伝子名称
4
UNQ492/PRO1008
遺伝子名称
5
UNQ682/PRO1316
遺伝子名称
10
hDkk-1
遺伝子名称
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意味 |
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Text is available under Creative Commons Attribution-ShareAlike (CC-BY-SA) and/or GNU Free Documentation License (GFDL). Weblio英和・和英辞典に掲載されている「Wiktionary英語版」の記事は、Wiktionaryのdickkopf (改訂履歴)の記事を複製、再配布したものにあたり、Creative Commons Attribution-ShareAlike (CC-BY-SA)もしくはGNU Free Documentation Licenseというライセンスの下で提供されています。 |
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