気がすむ
to be anxious about something
I am depressed in spirits―in low spirits―low-spirited.
to drive one mad―drive one distracted―drive one to distraction
to offend one―give offence
He is touched―cracked―crack-brained―unsound in mind―not in his right mind―out of his mind―out of his wits―out of his senses―off his head―not right in his head―wrong in the upper story―His wits are wandering―His reason wanders.
One's mind is on the stretch