出典:Wiktionary
出典:『Wiktionary』 (2025/10/28 20:27 UTC 版)
foki (plural fokis)
出典:Wikipedia
出典:『Wikipedia』 (2011/03/06 22:43 UTC 版)
The enzyme FokI, naturally found in Flavobacterium okeanokoites, is a bacterial type IIS restriction endonuclease consisting of an N-terminal DNA-binding domain and a non-specific DNA cleavage domain at the C-terminal. Once the protein is bound to duplex DNA via its DNA-binding domain at the 5'-GGATG-3': 5'-CATCC-3' recognition site, the DNA cleavage domain is activated and cleaves non-specifically between nine and 13 nucleotides downstream of the recognition site.