やっぱり本物は全然ちがうんですねの英語

They are (as) like as chalk and cheese.

radically different

There is definitely something wrong.

The facts are otherwise.

That is different from reality.

That's not the case.

It's emphatically not true.

〈事実ではない〉 That isn't true [so] at all.

especially not

I is not so.

to be disappointed of one's expectations―reckon without one's host

Totally wrong

Conditions are [The situation is] quite different in this country.

That's another thing

It's really different from what I expected.

No, sirree.

to be against reason―contrary to reason

No, you are wrong.

That is one thing, this is another thing.

That answer's wrong.

That is one thing; this is another thing.

This is an exact copy of the original.

That is of course different.

It's another story now.

That's another question [story].

Well, that's not true.

That is contrary to reason―against reason―illogical.

This is widely different from that.

That is completely different.

That's quite another thing to what you promised.