Progeriaとは 意味・読み方・使い方

発音

• 韻: -ɪɹiə
• 韻: -ɪəɹiə

名詞

progeria (countable かつ uncountable, 複数形 progerias)

1. (pathology) An extremely rare genetic condition wherein symptoms resembling aspects of aging are manifested at an early age.
   • 2004, E. S. Roach, “18: Hutchinson-Gilford progeria syndrome”, in E. Steve Roach; Van S. Miller, editors, Neurocutaneous Disorders, page 150:

     Hutchinson–Gilford syndrome or progeria (derived from pro, before, かつ geras, old age) is characterized by premature ageing (Fig. 18.1) and the early onset of age-related symptoms such as joint restriction and cerebral and myocardial infarction. Progeria occurs in about one in eight million people (DeBusk, 1972), but the true incidence may be somewhat higher (Sarkar かつ Shinton, 2001).

   • 2007, Carie Ann Braun; Cindy Miller Anderson, Pathophysiology: Functional Alterations in Human Health, page 436:

     Hutchinson-Gilford progeria is a syndrome commonly characterized by accelerated aging. Children affected by progeria have a life expectancy of approximately 13 years. Progeria results from damage to the LMNA gene that codes for the protein lamin A.

   • 2015, Ingrid A. Harten; Michelle Olive; Thomas N. Wright, “16: Vascular Disease in Hutchinson Gilford Progeria Syndrome and Aging: Common Phenotypes and Potential Mechanisms”, in Matt Kaeberlein; George Martin, editors, Handbook of the Biology of Aging, 8th edition, page 434:

     Hutchinson Gilford progeria syndrome (progeria) is a rare childhood disease, affecting 1 in 4 million births worldwide (Hennekam, 2006) and recapitulates certain aspects of the normal aging process at an accelerated rate.

同意語

• (genetic condition exhibiting symptoms of aging at an early age): Hutchinson-Gilford progeria, Hutchinson–Gilford syndrome

参考

• Werner syndrome